Coincident with the prestigious Nobel Prizes awarded each year are their parody counterparts: the Ig Nobel Prizes (a play on the words “ignoble” and “Nobel”). The honors are bestowed to individuals who demonstrate notable achievements that “first make people laugh, and then make them think.” The awards ceremonies take place each October at the Sanders Theater of Harvard University and include genuine Nobel Laureates presenting the awards.

This year’s Ig Nobel Prize in Medicine goes to Donald L. Unger of Thousand Oaks, California, for investigating whether knuckle cracking causes arthritis. The premise of his research, published in Arthritis & Rheumatism, was to test the validity of admonitions from “renowned authorities” (i.e., his mother, several aunts, and mother-in-law) that cracking his knuckles would lead to arthritis. Over the course of 50 years, Unger cracked the knuckles of his left hand at least twice daily, while sparing his right hand to serve as a control. At the end of the 50-year observation period, Unger did not detect any difference between both hands. He concluded that “there is no apparent relationship between knuckle cracking and the subsequent development of arthritis of the fingers.”

In light of the present evidence, Unger now questions whether other “parental beliefs”, such as the importance of eating spinach, are similarly flawed.

• Source
• Unger DL. Does knuckle cracking lead to arthritis of the fingers? Arthritis Rheum 1998;41:949-50.

The 2009 World Stem Cell Summit, co-sponsored by Johns Hopkins Medicine, begins today and continues until September 23 in Baltimore, Maryland. The conference assembles key experts in the science, ethics, policy, and business of stem cell research with an expected audience of over 1,200 participants from more than 25 countries. Among the diverse topics, there will be robust discussion about reprogrammed stem cells (iPSCs) and their use alongside embryonic stem cells in regenerative medicine.

The summit organizers have employed traditional and social networking technologies to disseminate information and updates, such as a website, news blog, Twitter site, and video (shown below).

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With the national push toward electronic medical records, there have been active efforts to upgrade clinical data and systems software. At some institutions, an effect of this transition is the migration from the traditional voice dictation systems or paper clinic notes to a typed electronic record.

A recent study at the University of Toronto Faculty of Medicine sought to evaluate the overall quality of electronic discharge summaries (EDS) compared to their traditional dictated counterparts. The measure for quality was based on a 100-point visual analogue scale rating the satisfaction of primary care physicians (PCPs) who receive the discharge summaries. Other endpoints studied included the satisfaction of house officers using either system (again, using a 100-point visual analogue scale), adverse outcomes after discharge (combined emergency department visits, readmissions, and death), and patient understanding of the discharge details.

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Tea consumption began in China around 2737 B.C. and has since become a staple among Asian and English cultures. The use of tea for medicinal purposes have prevailed for centuries in traditional Chinese medicine, but only recently gained prominence in the modern “alternative medicine” community. There has been increased interest and active biomedical research on tea extracts, with dozens of peer-reviewed scientific articles published each month exploring the health properties of green tea. Through in vitro and animal studies, green tea (derived from the Camellia sinensis plant) and its polyphenol compounds — in particular, epigallocatechin-3-gallate (EGCG) — have been associated with possible risk reductions in some cardiovascular, neurologic, and oncologic disorders. Human trials are however sparse or equivocal.

I previously reported on a Japanese study correlating green tea consumption with a lower prevalence of cognitive dysfunction. A similar research group from the Tohoku University School of Medicine (Sendai, Japan) has continued to analyze the benefits of green tea with other health outcomes: causes of mortality, cardiovascular disease, pneumonia, and cancers. Their most recent study, published in the American Journal of Epidemiology, evaluated the influence of green tea consumption on the development of hematologic malignancies.

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The advent of the Internet and Web 2.0 (for what it’s worth) has stimulated a movement for open information sharing and has heralded the migration from subscription-based paper publications to their more accessible–and free–digital counterparts. Notable by-products of this change include sites such as Wikipedia, NCBI Bookshelf, and the Johns Hopkins OpenCourseWare. Traditional academic journals have also begun to embrace this culture of open exchange, with a rapidly growing list of open access peer-reviewed publications on the Internet. Some journals opt to make their archived articles freely available a certain period after publication.
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